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The Rick Simpson Oil 60-gram protocol is the cornerstone of Rick Simpson’s recommended regimen. This 90-day (approximately 12-week) plan involves consuming exactly 60 grams of high-potency RSO to potentially achieve maximum therapeutic effects.
In 2025, many still follow or adapt this intensive schedule for serious wellness goals. The protocol emphasizes gradual dosage increases to build tolerance while minimizing side effects.
This guide provides the complete timeline, week-by-week breakdown, visual chart, tips for success, and essential safety notes. The protocol is demanding—consult a healthcare professional before starting.
Overview of the 60-Gram Protocol
Rick Simpson designed the regimen to reach 1 gram of RSO per day after building tolerance. Total consumption: ~60 grams over 90 days.
Three phases:
- Weeks 1-4: Micro-dosing to acclimate.
- Weeks 5-8: Steady ramp-up.
- Weeks 9-12: Full 1g daily maintenance.
Requires ~60-65 grams total (accounting for minor waste).
Full Schedule and Timeline
Weeks 1-4: Tolerance Building Phase
Start extremely small—most feel effects immediately.
- Week 1: Half rice grain (~0.025g) 3x/day → Total ~0.075g/day
- Week 2: Full rice grain (~0.05g) 3x/day → Total ~0.15g/day
- Week 3: Double to ~0.1g 3x/day → Total ~0.3g/day
- Week 4: Increase to ~0.15-0.2g 3x/day → Total ~0.45-0.6g/day
Cumulative used by end of Week 4: ~5-7 grams.
Weeks 5-8: Acceleration Phase
Double every 3-4 days as tolerated.
- Week 5: ~0.2-0.3g 3x/day → Total ~0.6-0.9g/day
- Week 6: ~0.3-0.4g 3x/day → Total ~0.9-1.2g/day (approach 1g)
- Week 7-8: Stabilize at 1g total daily, split 2-3 doses
Cumulative by end of Week 8: ~20-25 grams.
Weeks 9-12: Full Maintenance Phase
- Daily: 1 gram total (e.g., 0.5g morning + 0.5g evening, or 3x 0.33g)
- Continue for remaining ~35-40 grams
Total at completion: ~60 grams.
60-Gram Protocol Dosage Timeline Chart
| Week | Daily Total | Doses Per Day | Dose Size | Cumulative Grams Used |
|---|---|---|---|---|
| 1 | 0.075g | 3 | 0.025g | ~0.5g |
| 2 | 0.15g | 3 | 0.05g | ~1.5g |
| 3 | 0.3g | 3 | 0.1g | ~3.6g |
| 4 | 0.5-0.6g | 3 | 0.15-0.2g | ~7g |
| 5 | 0.7-0.9g | 3 | 0.25-0.3g | ~13g |
| 6-8 | 1g | 2-3 | 0.33-0.5g | ~25-30g |
| 9-12 | 1g | 2-3 | 0.33-0.5g | 60g total |
Tips for Following the Protocol Successfully
- Administration: Oral, sublingual, or capsules. Take with fatty food.
- Tracking: Journal dose, time, effects daily.
- Tolerance Signs: Reduced psychoactivity indicates readiness to increase.
- Lifestyle: Healthy diet, hydration, rest support process.
Quality RSO is critical—explore options at RSO Healing Hub.
Safety and Modifications
The full protocol is intense—many modify:
- Extend early weeks.
- Cap at 0.5g/day if 1g too strong.
- Add CBD to balance.
Watch for side effects: drowsiness, anxiety (reduce dose).
Not suitable for everyone—medical supervision recommended.
For complementary natural support, visit Magic Mushroom Store.
Frequently Asked Questions
- Total time exactly 90 days? Approximately—adjust to your pace.
- What after 60 grams? Simpson suggested 1-2g monthly maintenance.
- Can I split doses unevenly? Yes—consistency matters more.
Conclusion
The Rick Simpson Oil 60-gram protocol offers a structured 90-day timeline for high-dose consumption. Follow the schedule carefully, prioritize safety, and source quality product for best results in 2025.
Ready to stock up for the protocol?
Planning to try the 60-gram regimen? Share your questions in the comments!